Emad Tolba Selected Research

Polyphosphates

12/2020	The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor.
12/2020	The inorganic polymer, polyphosphate, blocks binding of SARS-CoV-2 spike protein to ACE2 receptor at physiological concentrations.
12/2020	Amorphous Polyphosphate and Ca-Carbonate Nanoparticles Improve the Self-Healing Properties of both Technical and Medical Cements.
12/2020	Amplified morphogenetic and bone forming activity of amorphous versus crystalline calcium phosphate/polyphosphate.
10/2020	Nanoparticle-directed and ionically forced polyphosphate coacervation: a versatile and reversible core-shell system for drug delivery.
5/2020	Self-Healing Properties of Bioinspired Amorphous CaCO3/Polyphosphate-Supplemented Cement.
1/2020	A physiologically active interpenetrating collagen network that supports growth and migration of epidermal keratinocytes: zinc-polyP nanoparticles integrated into compressed collagen.
6/2019	Transformation of Construction Cement to a Self-Healing Hybrid Binder.
1/2019	In Situ Polyphosphate Nanoparticle Formation in Hybrid Poly(vinyl alcohol)/Karaya Gum Hydrogels: A Porous Scaffold Inducing Infiltration of Mesenchymal Stem Cells.
1/2019	Biomimetic transformation of polyphosphate microparticles during restoration of damaged teeth.

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Emad Tolba Research Topics

Disease

30	Polyps 12/2020 - 01/2014
4	Wounds and Injuries (Trauma) 11/2020 - 09/2015
2	Hypersensitivity (Allergy) 03/2017 - 01/2016
2	Osteoporosis 01/2017 - 01/2017
1	Thrombosis (Thrombus) 10/2021
1	Flushing 12/2020
1	COVID-19 12/2020
1	Osteosarcoma (Osteogenic Sarcoma) 10/2020
1	Dental Caries (Decay, Dental) 01/2019
1	Bone Diseases (Bone Disease) 01/2017

Drug/Important Bio-Agent (IBA)

29	PolyphosphatesIBA 12/2020 - 01/2014
17	PolymersIBA 12/2020 - 02/2015
13	CalciumIBA 12/2020 - 06/2015
10	Phosphates (Orthophosphate)IBA 12/2020 - 06/2015
9	Alkaline PhosphataseIBA 12/2020 - 06/2015
6	IonsIBA 11/2020 - 06/2015
5	Durapatite (Hydroxylapatite)IBA 12/2020 - 06/2015
5	SaltsIBA 10/2020 - 01/2017
5	MineralsIBA 01/2019 - 01/2014
4	Proteins (Proteins, Gene)FDA Link 12/2020 - 02/2016
4	AlginatesIBA 11/2020 - 01/2014
4	CollagenIBA 01/2020 - 06/2015
3	Biocompatible Materials (Biomaterials)IBA 10/2021 - 01/2017
3	Adenosine Triphosphate (ATP)IBA 12/2020 - 06/2015
3	Silicon Dioxide (Silica)FDA LinkGeneric 12/2020 - 01/2014
3	HydrogelsIBA 11/2020 - 01/2014
3	GelatinIBA 11/2020 - 01/2014
3	Calcium Carbonate (Limestone)FDA Link 05/2020 - 01/2016
3	methylallyl trisulfide (MATS)IBA 01/2020 - 09/2015
3	ToothpastesIBA 01/2019 - 01/2017
3	EnzymesIBA 10/2018 - 06/2015
3	calcium phosphateIBA 01/2017 - 01/2016
2	Basic Amino Acids (Basic Amino Acid)IBA 12/2020 - 12/2020
2	CarbonatesIBA 12/2020 - 01/2016
2	SolutionsIBA 12/2020 - 01/2015
2	Ascorbic Acid (Vitamin C)FDA LinkGeneric 10/2020 - 06/2015
2	Dexamethasone (Maxidex)FDA LinkGeneric 10/2020 - 06/2015
2	Peptides (Polypeptides)IBA 01/2020 - 01/2018
2	Phosphorus (Red Phosphorus)IBA 01/2019 - 01/2016
2	Biopolymers (Biopolymer)IBA 01/2018 - 01/2015
2	Calcium Chloride (Calcium Chloride, Anhydrous)FDA LinkGeneric 03/2017 - 02/2016
2	Polylactic Acid-Polyglycolic Acid CopolymerIBA 01/2017 - 01/2016
2	Vitamin A (Retinol)FDA LinkGeneric 09/2015 - 06/2015
1	wintergreen oilIBA 10/2021
1	SARS-CoV-2 spike proteinIBA 12/2020
1	Arginine (L-Arginine)FDA Link 12/2020
1	tricalcium phosphateIBA 12/2020
1	Bone Cements (Bone Glue)IBA 12/2020
1	Angiotensin-Converting Enzyme 2IBA 12/2020
1	calcium silicate (Wollastonite)IBA 12/2020
1	metaperiodate (periodate)IBA 11/2020
1	Schiff Bases (Schiff Base)IBA 11/2020
1	Pharmaceutical PreparationsIBA 10/2020
1	ZincIBA 01/2020
1	Biological ProductsIBA 01/2020
1	Smart MaterialsIBA 01/2020
1	CryogelsIBA 01/2019
1	Karaya Gum (Gum, Karaya)FDA Link 01/2019
1	Artificial SalivaIBA 01/2019
1	MRS 2211IBA 10/2018
1	Adenylate KinaseIBA 10/2018
1	Levamisole (Decaris)FDA Link 10/2018
1	P(1),P(5)- di(adenosine- 5'- )pentaphosphateIBA 10/2018
1	Trifluoperazine (Stelazine)FDA LinkGeneric 10/2018
1	Chondroitin Sulfates (Chondroitin Sulfate)IBA 06/2017
1	Triclosan (pHisoHex)FDA Link 03/2017
1	Anti-Bacterial Agents (Antibiotics)IBA 03/2017
1	retinol acetateIBA 03/2017
1	FlavonoidsIBA 01/2017
1	Dentifrices (Dentifrice)IBA 01/2017
1	baicaleinIBA 01/2017
1	Type C PhospholipasesIBA 01/2017
1	Adenosine Triphosphatases (ATPase)IBA 01/2017
1	SodiumIBA 01/2017
1	StrontiumIBA 01/2017
1	flavoneIBA 01/2017
1	baicalinIBA 01/2017
1	Glucuronic Acid (Glucuronate)IBA 01/2017
1	FlavonesIBA 01/2017
1	Bone Morphogenetic Protein 2IBA 01/2017
1	Bone SubstitutesIBA 02/2016
1	Collagen Type I (Type I Collagen)IBA 02/2016
1	ammonium phosphate (diammonium phosphate)IBA 02/2016
1	Carbonic Anhydrases (Carbonic Anhydrase)IBA 01/2016
1	Oxygen (Dioxygen)IBA 01/2016
1	A 7 (A-7)IBA 01/2016
1	Bicarbonates (Hydrogen Carbonate)IBA 01/2016
1	CarbonIBA 01/2016
1	Carbonic Anhydrase IXIBA 01/2016
1	phosphorus pentoxideIBA 01/2016
1	Lactic Acid (Lactate)FDA LinkGeneric 01/2016
1	LeptinIBA 09/2015
1	AcidsIBA 09/2015
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 09/2015
1	Fatty Acid-Binding ProteinsIBA 09/2015
1	poly(lactide) (polylactic acid)IBA 09/2015

Therapy/Procedure

2	Microspheres (Microsphere) 01/2017 - 01/2016
2	Nanospheres 09/2015 - 06/2015
1	Chinese Traditional Medicine (Traditional Chinese Medicine) 01/2017
1	Therapeutics 01/2017